About Mark

Mark is our Director of Lower GI Physiology at The Functional Gut Clinic.

Mark holds a BSc in Physiology and Biology, and was awarded a PhD in Physiology/ Medicine from the University of London. Mark’s PhD research centred on “Prolonged monitoring of colonic motor activity by an ambulatory recording technique”. Mark has may years of experience, both clinical and academic, related to the physiological investigation of functional (primarily lower) gastrointestinal disorders.

Mark was integral to setting up the GI Physiology Unit at the Royal London Hospital in 1994 and is now Co-Director of the Unit. The Unit is internationally renowned, and provides a clinical service to more than 2,500 patients per year, which supplies the resources for aligned research; there are currently 20 full-time and affiliated staff members.

One of Mark’s principal research interests, particularly through collaboration with Professor Ian Cook (Sydney) and Dr Phil Dinning (Adelaide), is assessment of pancolonic motor function using novel methodologies. Mark also leads a flourishing research programme centered on clinical GI (principally colorectal) physiological investigation, together with Mr Peter Lunniss and Mr Charles Knowles. The programme originated from a fundamental philosophy of carefully phenotyping patients through comprehensive investigation and the group’s pioneering work on visceral hyposensitivity has now gained international recognition.


Mark is the author of over 80 peer-reviewed publications as well as 8 book chapters. Mark has also acted as Guest Editor for 2 journal supplements dedicated to the subject of chronic constipation.

If you have any queries or questions then please email us at admin@thefunctionalgutclinic.com